Abstract: The swift progress of Multi-modal Large Models (MLLMs) has showcased their impressive ability to tackle tasks blending vision and language.Yet, most current models and benchmarks cater to scenarios with a narrow scope of visual and textual contexts.These models often fall short when faced with complex comprehension tasks, which involve navigating through a plethora of irrelevant and potentially misleading information in both text and image forms.To bridge this gap, we introduce a new, more demanding task known as Interleaved Image-Text Comprehension (IITC).This task challenges models to discern and disregard superfluous elements in both images and text to accurately answer questions and to follow intricate instructions to pinpoint the relevant image.In support of this task, we further craft a new VEGA dataset, tailored for the IITC task on scientific content, and devised a subtask, Image-Text Association (ITA), to refine image-text correlation skills.Our evaluation of four leading closed-source models, as well as various open-source models using VEGA, underscores the rigorous nature of IITC.Even the most advanced models, such as Gemini-1.5-pro and GPT4V, only achieved modest success.By employing a multi-task, multi-scale post-training strategy, we have set a robust baseline for MLLMs on the IITC task, attaining an $85.8\%$ accuracy rate in image association and a $0.508$ Rouge score. These results validate the effectiveness of our dataset in improving MLLMs capabilities for nuanced image-text comprehension.